MMP14 anticorps (AA 470-499)

N° du produit ABIN3031714

Cet anticorps Souris Monoclonal détecte spécifiquement MMP14 dans WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MMP14 anticorps (AA 470-499) (ABIN3031714)

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 133CT15-10-5-1

Détail du produit anti-MMP14 anticorps

Épitope: AA 470-499

Fonction: MMP14 Antibody

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat, Bovine, Pig, Rabbit

Purification: Purified

Immunogène: A portion of amino acids 470-499 from the human protein was used as the immunogen for this MMP14 antibody.

Isotype: IgM

Information d'application

Indications d'application: Titration of the MMP14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MMP14 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MMP14

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Autre désignation: MMP14

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

UniProt: P50281

Pathways: Autophagy