NEU1 anticorps (AA 188-214)
Aperçu rapide pour NEU1 anticorps (AA 188-214) (ABIN3032558)
Antigène
Voir toutes NEU1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 188-214
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Réactivité croisée (Details)
- Expected species reactivity: Bovine
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 188-214 from the human protein was used as the immunogen for this NEU1 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the NEU1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the NEU1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
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Autre désignation
- NEU1
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Sujet
- The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.
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UniProt
- Q99519
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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