MAP3K14 anticorps (AA 119-148)
Aperçu rapide pour MAP3K14 anticorps (AA 119-148) (ABIN3031848)
Antigène
Voir toutes MAP3K14 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 119-148
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Purification
- Purified
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Immunogène
- A portion of amino acids 119-148 from the human protein was used as the immunogen for this NIK antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the NIK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the NIK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
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Autre désignation
- NIK (NF-kappa-beta-Inducing Kinase)
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Sujet
- NIK (MAP3K14), a member of the Ser/Thr protein kinase family, binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
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UniProt
- Q99558
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Pathways
- Signalisation NF-kappaB, TCR Signaling
Antigène
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