NPM1 anticorps (AA 7-33)
Aperçu rapide pour NPM1 anticorps (AA 7-33) (ABIN3032075)
Antigène
Voir toutes NPM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 7-33
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Réactivité croisée (Details)
- Expected species reactivity: Mouse, Rat
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Purification
- Purified
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Immunogène
- A portion of amino acids 7-33 from the human protein was used as the immunogen for this NPM1 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the NPM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the NPM1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
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Autre désignation
- NPM1
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Sujet
- Nucleophosmin/NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia.
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UniProt
- P06748
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Antigène
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