PCNA anticorps (AA 231-261)
Aperçu rapide pour PCNA anticorps (AA 231-261) (ABIN3032321)
Antigène
Voir toutes PCNA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 231-261
-
Réactivité croisée (Details)
- Expected species reactivity: Rat, Bovine, Primate, Hamster
-
Purification
- Purified
-
Immunogène
- A portion of amino acids 231-261 from the human protein was used as the immunogen for this PCNA antibody.
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- Titration of the PCNA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Aliquot the PCNA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
-
Autre désignation
- PCNA
-
Sujet
- PCNA is found in the nucleus and is a cofactor of DNA polymerase delta. This protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.
-
UniProt
- P12004
-
Pathways
- Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
Antigène
-