KIT anticorps (pTyr578)

N° du produit ABIN3031699

Cet anticorps Lapin Polyclonal détecte spécifiquement KIT dans ELISA et DB. Il présente une réactivité envers Humain.

Aperçu rapide pour KIT anticorps (pTyr578) (ABIN3031699)

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIT est non-conjugé

Application: ELISA, Dot Blot (DB)

Détail du produit anti-KIT anticorps

Épitope: pTyr578

Réactivité croisée (Details): Expected species reactivity: Bovine, Chicken, Mouse, Pig

Purification: Antigen affinity purified

Immunogène: This phospho-c-Kit antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY578 of human c-Kit.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the phospho-c-Kit antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the phospho-c-Kit antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur KIT

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Autre désignation: C-Kit

Sujet: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P10721

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity