SMAD4 anticorps (pThr277)

N° du produit ABIN3032606

L’anticorps anti-SMAD4 Polyclonal Lapin est utilisé pour la détection de SMAD4 dans des échantillons de Humain. Il a été validé pour IHC, ELISA, IF et DB.

Aperçu rapide pour SMAD4 anticorps (pThr277) (ABIN3032606)

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD4 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Dot Blot (DB)

Détail du produit anti-SMAD4 anticorps

Épitope: pThr277

Fonction: Phospho-SMAD4 Antibody (pT277)

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat

Purification: Antigen affinity

Immunogène: This phospho-SMAD4 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT277 of human SMAD4.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the phospho-SMAD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot the phospho-SMAD4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SMAD4

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Autre désignation: SMAD4

Sujet: Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

UniProt: Q13485

Pathways: Cycle Cellulaire, Chromatin Binding, Autophagy