PIN1 anticorps

N° du produit ABIN3032175

Cet anticorps anti-PIN1 Monoclonal Souris (Clone 855CT1-7-5) (ABIN3032175) détecte spécifiquement PIN1 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PIN1 anticorps (ABIN3032175)

Antigène: PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PIN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 855CT1-7-5

Détail du produit anti-PIN1 anticorps

Purification: Purified

Immunogène: Purified His-tagged protein was used to produced this monoclonal PIN1 antibody.

Isotype: IgG1

Information d'application

Indications d'application: Titration of the PIN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:25,Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PIN1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur PIN1

Antigène: PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))

Autre désignation: PIN1

Sujet: Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.

UniProt: Q13526