PRMT5 anticorps (AA 473-499)

N° du produit ABIN3032361

Cet anticorps anti-PRMT5 est un anticorps Lapin Polyclonal détectant PRMT5 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour PRMT5 anticorps (AA 473-499) (ABIN3032361)

Antigène: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRMT5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PRMT5 anticorps

Épitope: AA 473-499

Réactivité croisée (Details): Expected species reactivity: Mouse, Bovine, Primate, Xenopus

Purification: Purified

Immunogène: A portion of amino acids 473-499 from the human protein was used as the immunogen for this PRMT5 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the PRMT5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PRMT5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur PRMT5

Antigène: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Autre désignation: PRMT5

Sujet: Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

UniProt: O14744

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development