Progesterone Receptor anticorps (Isoform A)

N° du produit ABIN3032310

Cet anticorps anti-Progesterone Receptor Monoclonal Souris (Clone 312CT8-2-1-6) (ABIN3032310) détecte spécifiquement Progesterone Receptor dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Progesterone Receptor anticorps (Isoform A) (ABIN3032310)

Antigène: Progesterone Receptor (PGR)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Progesterone Receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 312CT8-2-1-6

Détail du produit anti-Progesterone Receptor anticorps

Épitope: AA 349-377, Isoform A

Fonction: Progesterone Receptor Antibody / Isoform A & B

Purification: Purified

Immunogène: A portion of amino acids 349-377 from the human protein was used as the immunogen for this Progesterone Receptor antibody.

Isotype: IgM, kappa

Information d'application

Indications d'application: Titration of the Progesterone Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Progesterone Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Progesterone Receptor

Antigène: Progesterone Receptor (PGR)

Autre désignation: Progesterone Receptor

Sujet: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration