PTBP1 anticorps (AA 26-55)

N° du produit ABIN3032275

Cet anticorps Lapin Polyclonal détecte spécifiquement PTBP1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PTBP1 anticorps (AA 26-55) (ABIN3032275)

Antigène: PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTBP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PTBP1 anticorps

Épitope: AA 26-55

Fonction: PTBP1 Antibody

Réactivité croisée (Details): Expected species reactivity: Bovine

Purification: Antigen affinity

Immunogène: A portion of amino acids 26-55 from the human protein was used as the immunogen for this PTBP1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the PTBP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PTBP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PTBP1

Antigène: PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

Autre désignation: PTBP1

Sujet: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.

UniProt: P26599

Pathways: Regulation of Muscle Cell Differentiation