RAD51C anticorps (AA 169-198)

N° du produit ABIN3032429

L’anticorps anti-RAD51C Polyclonal Lapin est utilisé pour la détection de RAD51C dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour RAD51C anticorps (AA 169-198) (ABIN3032429)

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51C est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RAD51C anticorps

Épitope: AA 169-198

Fonction: RAD51C Antibody

Purification: Antigen affinity

Immunogène: A portion of amino acids 169-198 from the human protein was used as the immunogen for this RAD51C antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the RAD51C antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the RAD51C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur RAD51C

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Autre désignation: RAD51C

Sujet: This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

UniProt: O43502

Pathways: Réparation de l'ADN