RAGE anticorps (AA 76-104)
Aperçu rapide pour RAGE anticorps (AA 76-104) (ABIN3029883)
Antigène
Voir toutes RAGE (AGER) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 76-104
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 76-104 from the mouse protein was used as the immunogen for this Rage antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the Rage antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Rage antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
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Autre désignation
- Rage
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Sujet
- RAGE, the 'receptor for advanced glycation endproducts' is a transmembrane receptor of the immunoglobulin super family. The interaction between RAGE and its ligands, AGE and HMGB1, is thought to result in pro-inflammatory gene activation. Due to an enhanced level of RAGE ligands in diabetes or other chronic disorders, this receptor is hypothesised to have a causative effect in a range of inflammatory diseases such as diabetic complications, Alzheimer's disease and even some tumors. [Wiki]
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UniProt
- Q9WVS4
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Pathways
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
Antigène
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