Rhodopsin anticorps (AA 310-339)

N° du produit ABIN3032473

Cet anticorps Lapin Polyclonal détecte spécifiquement Rhodopsin dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Rhodopsin anticorps (AA 310-339) (ABIN3032473)

Antigène: Rhodopsin (RHO)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Rhodopsin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Rhodopsin anticorps

Épitope: AA 310-339

Réactivité croisée (Details): Expected species reactivity: Primate

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 310-339 from human Rhodopsin was used as the immunogen for this RHO antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the RHO antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the RHO antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Rhodopsin

Antigène: Rhodopsin (RHO)

Autre désignation: rho (Rhodopsin)

Classe de substances: Chemical

Sujet: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.

UniProt: P08100

Pathways: Signalisation WNT, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction