Sonic Hedgehog anticorps (AA 395-450)
Aperçu rapide pour Sonic Hedgehog anticorps (AA 395-450) (ABIN3029025)
Antigène
Voir toutes Sonic Hedgehog (SHH) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 395-450
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 395-450 were used as immunogen for this Shh antibody.
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Isotype
- Ig Fraction
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Indications d'application
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Titration of the Shh antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. The 45 kDa precursor protein autocleaves into 27 kDa amino and 19 kDa carboxy fragments.\. Flow Cytometry: 1:25,Western blot: 1:1000 (1)
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Shh antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Sonic Hedgehog (SHH)
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Autre désignation
- Shh
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Sujet
- Sonic hedgehog binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO.
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UniProt
- Q62226
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Pathways
- Signalisation Hedgehog, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Antigène
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