SOCS4 anticorps (AA 227-254)

N° du produit ABIN3029046

Cet anticorps anti-SOCS4 Polyclonal Lapin (ABIN3029046) détecte spécifiquement SOCS4 dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SOCS4 anticorps (AA 227-254) (ABIN3029046)

Antigène: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SOCS4 anticorps

Épitope: AA 227-254

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 227-254 from the human protein was used as the immunogen for this SOCS4 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the SOCS4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SOCS4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur SOCS4

Antigène: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Autre désignation: SOCS4

Sujet: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. [UniProt]

UniProt: Q8WXH5

Pathways: Signalistation JAK/STAT, EGFR Signaling Pathway