SUV39H2 anticorps (AA 93-122)

N° du produit ABIN3029055

Cet anticorps anti-SUV39H2 Polyclonal Lapin (ABIN3029055) détecte spécifiquement SUV39H2 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour SUV39H2 anticorps (AA 93-122) (ABIN3029055)

Antigène: SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUV39H2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SUV39H2 anticorps

Épitope: AA 93-122

Fonction: SUV39H2 Antibody (KMT1B)

Purification: Purified

Immunogène: A portion of amino acids 93-122 from the human protein was used as the immunogen for this KMT1B / SUV39H2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the SUV39H2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SUV39H2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SUV39H2

Antigène: SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))

Autre désignation: SUV39H2

Sujet: The murine gene Suv39h2/kmt1b encodes an H3 histone methyltransferase (HMTase) 59 % identical in sequence to mouse Suv39h1. During embryogenesis, both proteins overlap in tissue expression, yet Suv39h2 transcripts are restricted to the testes in adult animals. Immunolocalization of the Suv39h2 protein during spermatogenesis indicates enrichment at the heterochromatin from the leptotene to the round spermatid stage. Moreover, Suv39h2 specifically accumulates with chromatin of the sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase. Suv39h2 HMTase may also organize meiotic heterochromatin with the potential for epigenetic imprint to the male germline.

UniProt: Q9H5I1