TBK1 anticorps (AA 8-35)

N° du produit ABIN3029093

L’anticorps Lapin Polyclonal anti-TBK1 a été validé pour WB et ELISA. Il convient pour détecter TBK1 dans des échantillons de Souris.

Aperçu rapide pour TBK1 anticorps (AA 8-35) (ABIN3029093)

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TBK1 anticorps

Épitope: AA 8-35

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 8-35 from the mouse protein was used as the immunogen for this Tbk1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Tbk1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Tbk1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TBK1

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Autre désignation: Tbk1

Sujet: Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.

UniProt: Q9WUN2

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome