TBK1 anticorps (AA 150-181)

N° du produit ABIN3029094

Cet anticorps anti-TBK1 est un anticorps Lapin Polyclonal détectant TBK1 dans WB, ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour TBK1 anticorps (AA 150-181) (ABIN3029094)

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-TBK1 anticorps

Épitope: AA 150-181

Réactivité croisée (Details): Expected species reactivity: Mouse, Xenopus

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 150-181 from the human protein was used as the immunogen for this TBK1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the TBK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the TBK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TBK1

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Autre désignation: TBK1

Sujet: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TKB is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK.

UniProt: Q9UHD2

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome