TLR2 anticorps (AA 212-242)

N° du produit ABIN3029164

Détail du produit anti-TLR2 anticorps

Antigène: TLR2 (Toll-Like Receptor 2 (TLR2))

Épitope: AA 212-242

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Réactivité croisée (Details): Expected species reactivity: Primate

Purification: Purified

Immunogène: A portion of amino acids 212-242 from the human protein was used as the immunogen for this TLR2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the TLR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the TLR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TLR2

Antigène: TLR2 (Toll-Like Receptor 2 (TLR2))

Autre désignation: TLR2 (TLR2 Produits)

Synonymes: anticorps CD282, anticorps TIL4, anticorps Ly105, anticorps toll like receptor 2, anticorps toll-like receptor 2, anticorps TLR2, anticorps Tlr2, anticorps tlr2

Sujet: TLR2 cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. [UniProt]

UniProt: O60603

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades