TLR2 anticorps (AA 281-310)

N° du produit ABIN657617

Détail du produit anti-TLR2 anticorps

Antigène: TLR2 (Toll-Like Receptor 2 (TLR2))

Épitope: AA 281-310

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the Central region of human TLR2.

Clone: RB33608

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: TLR2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur TLR2

Antigène: TLR2 (Toll-Like Receptor 2 (TLR2))

Autre désignation: TLR2 (TLR2 Produits)

Synonymes: anticorps CD282, anticorps TIL4, anticorps Ly105, anticorps toll like receptor 2, anticorps toll-like receptor 2, anticorps TLR2, anticorps Tlr2, anticorps tlr2

Sujet: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Poids moléculaire: 89838

ID gène: 7097

NCBI Accession: NP_003255

UniProt: O60603

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades