PLAT anticorps (AA 371-399)
Aperçu rapide pour PLAT anticorps (AA 371-399) (ABIN3032243)
Antigène
Voir toutes PLAT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 371-399
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Purification
- Purified
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Immunogène
- A portion of amino acids 371-399 from the human protein was used as the immunogen for this tPA antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the tPA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the tPA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PLAT (Plasminogen Activator, Tissue (PLAT))
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Autre désignation
- TPA
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Sujet
- TPA is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism.
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UniProt
- P00750
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Pathways
- Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
Antigène
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