PLAT anticorps (AA 371-399)

N° du produit ABIN3032243

Détail du produit anti-PLAT anticorps

Antigène: PLAT (Plasminogen Activator, Tissue (PLAT))

Épitope: AA 371-399

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAT est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: Purified

Immunogène: A portion of amino acids 371-399 from the human protein was used as the immunogen for this tPA antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the tPA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the tPA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur PLAT

Antigène: PLAT (Plasminogen Activator, Tissue (PLAT))

Autre désignation: TPA (PLAT Produits)

Synonymes: anticorps T-PA, anticorps TPA, anticorps AU020998, anticorps AW212668, anticorps D8Ertd2e, anticorps tPA, anticorps PATISS, anticorps tpa, anticorps Plat, anticorps plat, anticorps t-pa, anticorps plasminogen activator, tissue type, anticorps plasminogen activator, tissue, anticorps chromosome 20 open reading frame 181, anticorps plasminogen activator, tissue L homeolog, anticorps PLAT, anticorps Plat, anticorps plat, anticorps C20orf181, anticorps plat.L

Sujet: TPA is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism.

UniProt: P00750

Pathways: Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome