VEGFA anticorps (AA 66-95)

N° du produit ABIN3029576

L’anticorps Lapin Polyclonal anti-VEGFA a été validé pour WB et ELISA. Il convient pour détecter VEGFA dans des échantillons de Humain.

Aperçu rapide pour VEGFA anticorps (AA 66-95) (ABIN3029576)

Antigène: VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VEGFA est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-VEGFA anticorps

Épitope: AA 66-95

Purification: Purified

Immunogène: A portion of amino acids 66-95 from the human protein was used as the immunogen for this VEGFA antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the VEGFA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the VEGFA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur VEGFA

Antigène: VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Autre désignation: VEGFA

Sujet: VEGFA is a member of the PDGF/VEGF growth factor family and and is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGFA have been associated with proliferative and nonproliferative diabetic retinopathy.

UniProt: P15692

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling