ATG10 anticorps (C-Term)

N° du produit ABIN497986

Cet anticorps Lapin Polyclonal détecte spécifiquement ATG10 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ATG10 anticorps (C-Term) (ABIN497986)

Antigène: ATG10 (Autophagy Related 10 (ATG10))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG10 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ATG10 anticorps

Épitope: C-Term

Specificité: Recognizes APG10L/ATG10 (C-term).

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse and Rat

Purification: Immunoaffinity Chromatography

Immunogène: ATG10 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of Human ATG10 (Genbank accession No. EAW95884).

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: ATG10 antibody can be used for the detection of ATG10 at 0.5-1 μg/mL. Positive Control: SK-N-SH Cell Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ATG10

Antigène: ATG10 (Autophagy Related 10 (ATG10))

Autre désignation: APG10L / ATG10

Sujet: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy protein family is ATG10, an E2-like enzyme involved in two ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugation and the modification of a soluble form of MAP-LC3, a homolog of yeast Apg8, to a membrane-bound form. ATG10 has also been shown to interact with ATG12 in human embryonic kidney cells in the presence of ATG7. Multiple isoforms of ATG10 are known to exist.Synonyms: Autophagy-related protein 10

ID gène: 83734

NCBI Accession: NP_001124500

UniProt: Q9H0Y0

Pathways: ER-Nucleus Signaling, Autophagy