ACLY anticorps

N° du produit ABIN498187

Détail du produit anti-ACLY anticorps

Antigène: ACLY (ATP Citrate Lyase (ACLY))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACLY est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificité: This antibody detects endogenous levels of ATP-citrate synthase protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ACLY

Antigène: ACLY (ATP Citrate Lyase (ACLY))

Autre désignation: ATP-Citrate Synthase (ACLY Produits)

Synonymes: anticorps ACLY, anticorps DDBDRAFT_0205389, anticorps DDBDRAFT_0235360, anticorps DDB_0205389, anticorps DDB_0235360, anticorps ACL, anticorps BcDNA:LD21334, anticorps CG8322, anticorps DmATPCL, anticorps Dmel\\CG8322, anticorps anon-WO0140519.179, anticorps dATPCL, anticorps l(2)01466, anticorps l(2)k09217, anticorps n(2)k09217, anticorps ATPCL, anticorps CLATP, anticorps A730098H14Rik, anticorps AW538652, anticorps Clatp, anticorps acly, anticorps cb722, anticorps zgc:92008, anticorps ATP citrate lyase, anticorps ATP citrate lyase S homeolog, anticorps ATP-citrate synthase, anticorps citrate synthase, mitochondrial, anticorps atp-citrate synthase, anticorps ATP citrate lyase a, anticorps ACLY, anticorps acly.S, anticorps LOC587157, anticorps acly, anticorps ATPCL, anticorps LOC5564509, anticorps CpipJ_CPIJ010291, anticorps Bm1_26245, anticorps ACL, anticorps Acly, anticorps aclya

Sujet: ATP citrate lyase (ACL) is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer of four identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. One of these products, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. NDPK has been found to phosphorylate ACL and insulin to increase phosphorylation of ACL.Synonyms: ACLY, ATP citrate (pro-S-)-lyase, Citrate cleavage enzyme

Poids moléculaire: approx. 120 kDa

ID gène: 47

NCBI Accession: NP_001087

UniProt: P53396

Pathways: L'effet Warburg