CD19 anticorps

N° du produit ABIN498242

L’anticorps anti-CD19 Polyclonal Lapin est utilisé pour la détection de CD19 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour CD19 anticorps (ABIN498242)

Antigène: CD19 (CD19 Molecule (CD19))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD19 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD19 anticorps

Specificité: This antibody detects endogenous levels of CD19 protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur CD19

Antigène: CD19 (CD19 Molecule (CD19))

Autre désignation: CD19

Sujet: CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin- like domains. CD19 is selectively expressed on the cell surface of B lymphocytes, where it activates intracellular signaling cascades involving both Ras and phosphatidylinositol 3-kinase pathways. Activation of CD19 results in cross-linking of the membrane protein immunoglobulin chains and the subsequent association with Src family protein tyrosine kinases (PTK). Expression of CD19 is continuous throughout B cell development and through terminal differentiation of B cells into plasma cells. CD19 forms functional complexes with B lymphocyte surface proteins, including integrin β1, CD21 and CD81, which are involved in regulating B cell development.Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12

Poids moléculaire: approx. 61 kDa

ID gène: 930

NCBI Accession: NP_001761

UniProt: P15391

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway