TNFSF9 anticorps

N° du produit ABIN498281

L’anticorps anti-TNFSF9 Polyclonal Lapin est utilisé pour la détection de TNFSF9 dans des échantillons de Humain. Il a été validé pour WB et IF.

Aperçu rapide pour TNFSF9 anticorps (ABIN498281)

Antigène: TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFSF9 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-TNFSF9 anticorps

Specificité: This antibody detects endogenous levels of 4-1BBL protein. (region surrounding Arg69)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TNFSF9

Antigène: TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))

Autre désignation: 4-1BBL / TNFSF9

Sujet: CD137, also designated ILA and 4-1BB in mouse, belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. CD137 is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. Crosslinking of the CD137 ligand induces apoptosis in resting lymphocytes. In contrast, CD137 regulates peripheral monocyte survival by inducing a cytokine release profile, and is mediated by M-CSF and to a lesser extent by granulocyte-macrophage colony-stimulating factor and IL-3. Soluble forms of CD137 are found in sera from patients with rheumatoid arthritis and may provide a negative control mechanism for immune responses.Synonyms: 4-1BB ligand, CD137L, Tumor necrosis factor ligand superfamily member 9

Poids moléculaire: approx. 23 kDa

ID gène: 8744

NCBI Accession: NP_003802

UniProt: P41273

Pathways: Activated T Cell Proliferation, Cancer Immune Checkpoints