HTR1F anticorps

N° du produit ABIN498368

L’anticorps anti-HTR1F Polyclonal Lapin est utilisé pour la détection de HTR1F dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et IF.

Aperçu rapide pour HTR1F anticorps (ABIN498368)

Antigène: HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTR1F est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-HTR1F anticorps

Specificité: This antibody detects endogenous levels of SR-1F protein. (region surrounding Thr126)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunofluorscence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HTR1F

Antigène: HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

Autre désignation: Serotonin Receptor 1F (HTR1F)

Sujet: The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. beta-adrenergic bound to adrenaline activates adenylyl cyclase, while alpha2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the alpha2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1-7 (5HT1-7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.Synonyms: 5-HT-1F, 5-hydroxytryptamine receptor 1F, HTR1EL

Poids moléculaire: approx. 38 kDa

ID gène: 3355

NCBI Accession: NP_000857

UniProt: P30939

Pathways: Signalistation JAK/STAT