Serotonin Receptor 4 anticorps

N° du produit ABIN498370

Détail du produit anti-Serotonin Receptor 4 anticorps

Antigène: Serotonin Receptor 4 (HTR4)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of SR-4 protein. (region surrounding Asp47)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Serotonin Receptor 4

Antigène: Serotonin Receptor 4 (HTR4)

Autre désignation: Serotonin Receptor 4 / HTR4 (HTR4 Produits)

Synonymes: anticorps 5-HT4, anticorps 5-HT<4L>, anticorps 5HTR4, anticorps 5-HT4S, anticorps 5-HT4R, anticorps 5 hydroxytryptamine (serotonin) receptor 4, anticorps 5-hydroxytryptamine receptor 4, anticorps Htr4, anticorps HTR4

Sujet: Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. The gene which encodes SR-3 maps to human chromosome 11q23.1-q23.2. SR-4 mediates widespread effects in central and peripheral nervous systems. The gene which encodes SR-4 maps to human chromosome 5q31-q33. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.Synonyms: 5-HT-4, 5-HT4, 5-hydroxytryptamine receptor 4

Poids moléculaire: approx. 48 kDa

ID gène: 3360

NCBI Accession: NP_000861

UniProt: Q13639

Pathways: Signalistation JAK/STAT, cAMP Metabolic Process, S100 Proteins