Cyclin D1 anticorps
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- Antigène Voir toutes Cyclin D1 (CCND1) Anticorps
- Cyclin D1 (CCND1)
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Cyclin D1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects endogenous levels of Cyclin D1 protein (region surrounding Asp86)
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Pureté
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product CCND1 Anticorps primaire
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- Indications d'application
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Unveiling the optimal parameters for cellulolytic characteristics of Talaromyces verruculosus SGMNPf3 and its secretory enzymes." dans: Journal of applied microbiology, Vol. 119, Issue 1, pp. 88-98, (2016) (PubMed).
: "High-throughput screening system for inhibitors of human Heat Shock Factor 2." dans: Cell stress & chaperones, Vol. 20, Issue 5, pp. 833-41, (2016) (PubMed).
: "Gastric adenocarcinoma of the fundic gland type shares common genetic and phenotypic features with pyloric gland adenoma." dans: Pathology international, Vol. 63, Issue 6, pp. 318-25, (2015) (PubMed).
: "Potential of UCHL1 as biomarker for destruction of pancreatic beta cells." dans: Journal of proteomics, Vol. 117, pp. 156-67, (2015) (PubMed).
: "Correlation between tuberous sclerosis complex 2 and glycogen synthase kinase 3 beta levels, and outcomes of patients with hepatocellular carcinoma treated by hepatectomy." dans: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 44, Issue 11, pp. 1142-50, (2014) (PubMed).
: "Herbal formula Astragali Radix and Rehmanniae Radix exerted wound healing effect on human skin fibroblast cell line Hs27 via the activation of transformation growth factor (TGF-β) pathway and ..." dans: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 20, Issue 1, pp. 9-16, (2013) (PubMed).
: "Lewis y regulate cell cycle related factors in ovarian carcinoma cell RMG-I in vitro via ERK and Akt signaling pathways." dans: International journal of molecular sciences, Vol. 13, Issue 1, pp. 828-39, (2012) (PubMed).
: "Tracing putative trafficking of the glycolytic enzyme enolase via SNARE-driven unconventional secretion." dans: Eukaryotic cell, Vol. 11, Issue 8, pp. 1075-82, (2012) (PubMed).
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Unveiling the optimal parameters for cellulolytic characteristics of Talaromyces verruculosus SGMNPf3 and its secretory enzymes." dans: Journal of applied microbiology, Vol. 119, Issue 1, pp. 88-98, (2016) (PubMed).
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- Antigène
- Cyclin D1 (CCND1)
- Autre désignation
- Cyclin D1 (CCND1 Produits)
- Synonymes
- anticorps BCL1, anticorps D11S287E, anticorps PRAD1, anticorps U21B31, anticorps AI327039, anticorps CycD1, anticorps Cyl-1, anticorps bcl-1, anticorps cD1, anticorps cb161, anticorps cycd1, anticorps etID37810.7, anticorps fb52e01, anticorps fc45c08, anticorps fc83a12, anticorps id:ibd1198, anticorps wu:fb52e01, anticorps wu:fc45c08, anticorps wu:fc83a12, anticorps ccnd1b, anticorps prad1, anticorps ccnd1, anticorps ccnd1a, anticorps bcl1, anticorps d11s287e, anticorps u21b31, anticorps CCND1, anticorps cyclin D1, anticorps cyclin D1 S homeolog, anticorps cyclin D1 L homeolog, anticorps CCND1, anticorps Ccnd1, anticorps ccnd1, anticorps ccnd1.S, anticorps ccnd1.L
- Sujet
- Considerable effort directed towards the identification of G1 cyclins has led to the isolation of cyclin D, cyclin C and cyclin E. Of these, cyclin D corresponds to a putative human oncogene, designated PRAD1, which maps at the site of the Bcl1 rearrangement in certain lymphomas and leukemias. Two additional human type D cyclins, as well as their mouse homologs, have been identified. Evidence has established that members of the cyclin D family function to regulate phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors.Synonyms: BCL-1 oncogene, BCL1, CCND1, Cyclin-D1, G1/S-specific cyclin-D1, PRAD-1 oncogene, PRAD1
- Poids moléculaire
- approx. 36 kDa
- ID gène
- 595
- NCBI Accession
- NP_444284
- UniProt
- P24385
- Pathways
- Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
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