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Angiotensin I Converting Enzyme 1 anticorps

ACE Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN498506
  • Antigène Voir toutes Angiotensin I Converting Enzyme 1 (ACE) Anticorps
    Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
    Reactivité
    • 103
    • 54
    • 51
    • 22
    • 12
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 90
    • 30
    • 3
    • 1
    • 1
    Lapin
    Clonalité
    • 83
    • 42
    Polyclonal
    Conjugué
    • 61
    • 16
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Angiotensin I Converting Enzyme 1 est non-conjugé
    Application
    • 97
    • 45
    • 44
    • 31
    • 26
    • 26
    • 15
    • 10
    • 10
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    This antibody detects endogenous levels of BNIP-2 protein. (region surrounding Phe940)
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Mouse.
    Purification
    Affinity chromatography
    Pureté
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product ACE Anticorps primaire
  • Indications d'application
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
    Autre désignation
    ACE / CD143 (ACE Produits)
    Synonymes
    anticorps ACE1, anticorps CD143, anticorps DCP, anticorps DCP1, anticorps ICH, anticorps MVCD3, anticorps AW208573, anticorps Dcp1, anticorps StsRR92, anticorps dcp, anticorps ace1, anticorps dcp1, anticorps xace, anticorps cd143, anticorps ACE, anticorps angiotensin I converting enzyme, anticorps angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, anticorps angiotensin-converting enzyme, anticorps angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, anticorps angiotensin-converting enzyme-like, anticorps ACE, anticorps Ace, anticorps ace, anticorps CpipJ_CPIJ009106, anticorps ACE3, anticorps LOC101824864
    Sujet
    The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins.Synonyms: Angiotensin-converting enzyme, DCP, DCP1, Dipeptidyl carboxypeptidase I
    Poids moléculaire
    approx. 165 kDa
    ID gène
    1636
    NCBI Accession
    NP_000780
    UniProt
    P12821
    Pathways
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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