PAK3 anticorps
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- Antigène Voir toutes PAK3 Anticorps
- PAK3
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAK3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of PAKbeta protein. (region surrounding asn148)
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Pureté
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product PAK3 Anticorps primaire
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- Indications d'application
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- PAK3
- Autre désignation
- PAK3 (PAK3 Produits)
- Synonymes
- anticorps CDKN1A, anticorps MRX30, anticorps MRX47, anticorps OPHN3, anticorps PAK3beta, anticorps bPAK, anticorps hPAK3, anticorps PAK-3, anticorps Pak65alpha, anticorps Pak65beta, anticorps Stk4, anticorps beta-PAK, anticorps XPak3, anticorps bpak, anticorps cdkn1a, anticorps mrx30, anticorps mrx47, anticorps ophn3, anticorps pak3, anticorps pak3-A, anticorps pak3beta, anticorps p21 (RAC1) activated kinase 3, anticorps p21 protein (Cdc42/Rac)-activated kinase 3, anticorps p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog, anticorps PAK3, anticorps Pak3, anticorps pak3.L
- Sujet
- PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. PAK3 forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. It may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. A point mutation in this gene has been linked to nonsyndromic X-linked mental retardation.Synonyms: Beta-PAK, OPHN3, Oligophrenin-3, PAK 3, PAK beta, PAK-3, Serine/threonine-protein kinase PAK 3, p21-activated kinase 3
- Poids moléculaire
- approx. 70 kDa
- ID gène
- 5063
- NCBI Accession
- NP_001121645
- UniProt
- O75914
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