C1S anticorps

N° du produit ABIN499051

Cet anticorps Lapin Polyclonal détecte spécifiquement C1S dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour C1S anticorps (ABIN499051)

Antigène: C1S (Complement Component 1, S Subcomponent (C1S))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1S est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-C1S anticorps

Specificité: This antibody detects endogenous levels of C1s protein. (region surrounding Lys583)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur C1S

Antigène: C1S (Complement Component 1, S Subcomponent (C1S))

Autre désignation: C1s

Sujet: C1s proenzyme is a glycoprotein produced primarily by hepatocytes but also by other cells. The proenzyme is produced as a single chain polypeptide of 688 aa. Upon activation the peptide is cleaved between R437 and I438 giving the activated enzyme consisting of two disulfide-linked chains, A chain (52.2 kDa) and B chain (27.7 kDa). The Ca dependent catalytic subunit of the C1 complex (C1q, C1r, C1s) comprises of two C1s and two C1r molecules and this serine protease tetramer is responsible for the initial steps in the classical complement pathway, cleavage of C4 and C2.Synonyms: C1 esterase, Complement 1s, Complement C1s, Complement C1s subcomponent, Complement component 1 subcomponent s

Poids moléculaire: approx. 77 kDa

ID gène: 716

NCBI Accession: NP_001725

UniProt: P09871

Pathways: Système du Complément