C9 anticorps

N° du produit ABIN499053

Cet anticorps anti-C9 Polyclonal Lapin (ABIN499053) détecte spécifiquement C9 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour C9 anticorps (ABIN499053)

Antigène: C9 (Complement Component C9 (C9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C9 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-C9 anticorps

Specificité: This antibody detects endogenous levels of C9 protein. (region surrounding His216)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur C9

Antigène: C9 (Complement Component C9 (C9))

Autre désignation: Complement C9

Sujet: C9 is synthesised in the liver and monocytes, and is a plasma protein consisting of a single polypeptide chain of molecular weight 71 kDa. Normal plasma concentration is 60 mg/L. C9 forms part of the membrane attack complex (MAC) the cytolytic terminal complex of the complement pathways. C9 binds to the membrane associated C5b-8, binding of C9 to C5b-8 leads to the circular polymerisation of 12-18 C9 Molecules. This is the basis of the hydrophilic, proteinwalled, trans-membrane channel formed by the MAC, which leads to cell lysis and destruction.Synonyms: Complement 9, Complement component C9

Poids moléculaire: approx. 70 kDa

ID gène: 735

NCBI Accession: NP_001728

UniProt: P02748

Pathways: Système du Complément