POLD1 anticorps

N° du produit ABIN499061

L’anticorps anti-POLD1 Polyclonal Lapin est utilisé pour la détection de POLD1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB.

Aperçu rapide pour POLD1 anticorps (ABIN499061)

Antigène: POLD1 (Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLD1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-POLD1 anticorps

Specificité: This antibody detects endogenous levels of CNA pol delta cat protein. (region surrounding Asp1091)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity-Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: Western blot: 1: 500-1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur POLD1

Antigène: POLD1 (Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))

Autre désignation: POLD1

Sujet: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and togther with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds (By similarity).Synonyms: DNA polymerase delta catalytic subunit, DNA polymerase subunit delta p125

Poids moléculaire: approx. 125 kDa

ID gène: 5424

NCBI Accession: NP_002682

UniProt: P28340

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Chromatin Binding, Synthesis of DNA