ME1 anticorps
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- Antigène Voir toutes ME1 Anticorps
- ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ME1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects endogenous levels of Malic enzyme 1 protein. (region surrounding Tyr500)
- Réactivité croisée (Details)
- Species reactivity (expected):Mouse and RatSpecies reactivity (tested):Human.
- Purification
- Affinity chromatography using epitope-specific immunogen
- Pureté
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product ME1 Anticorps primaire
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- Indications d'application
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))
- Autre désignation
- NADP-ME (ME1 Produits)
- Synonymes
- anticorps HUMNDME, anticorps MES, anticorps D9Ertd267e, anticorps Mdh-1, anticorps Mod-1, anticorps Mod1, anticorps MOD1, anticorps ME1, anticorps zgc:153079, anticorps malic enzyme 1, anticorps malic enzyme 1, NADP(+)-dependent, cytosolic, anticorps ME1, anticorps Me1, anticorps me1
- Sujet
- ME1 (Malic enzyme 1), also known as NADP-ME, MES or HUMNDME, is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family. Expressed ubiquitously with highest expression in liver and white adipose tissue, ME1 functions as an NADP-dependent enzyme that catalyzes the conversion of S-malate and NADP to pyruvate, carbon dioxide and NADPH (a reducing agent that participates in fatty acid biosynthesis). Through its ability to catalyze the reversible oxidative decarboxylation of malate, ME1 links the citric acid and glycolytic cycles. ME1 exists as a homotetramer that uses divalent metal cations, such as magnesium or manganese, as cofactors. The expression of ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet, indicating that ME1 may play an important role as a housekeeping protein within the cell.Synonyms: ME1, NADP-dependent malic enzyme
- Poids moléculaire
- approx. 64 kDa
- ID gène
- 4199
- NCBI Accession
- NP_002386
- UniProt
- P48163
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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