SNAP23 anticorps (Internal Region)

N° du produit ABIN499144

Cet anticorps Chèvre Polyclonal détecte spécifiquement SNAP23 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain, Souris, Rat et Boeuf (Vache).

Aperçu rapide pour SNAP23 anticorps (Internal Region) (ABIN499144)

Antigène: SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SNAP23 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-SNAP23 anticorps

Épitope: Internal Region

Séquence: C-QIKRITDKAD

Specificité: This antibody is expected to recognize both reported isoforms (NP_003816.2 and NP_570710.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_003816.2 and NP_570710.1. Genename: SNAP23

Information d'application

Indications d'application: Peptide ELISA: Limit Dilution: 1/8000. Western blot: 0.1-0.3 μg/mL. This antibody detects a band of approx. 26 kDa Human Placentalysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SNAP23

Antigène: SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))

Autre désignation: SNAP23

Sujet: Synaptosomal-associated proteins (SNAPs) are cytosolic proteins that play a key role in in the process of membrane fusion in intracellular vesicle trafficking. In eukaryotic cells, the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex is critical to membrane docking and fusion and is believed to impart some degree of specificity between vesicle SNARE (v-SNARE) and target organelle SNARE (t-SNARE). In neurons and neuroendocrine cells, the SNARE complex consists of the integral membrane proteins VAMP (vesicle-associated membrane protein), syntaxin and SNAP-25. In non-neuronal tissue, a SNAP-25 homolog, SNAP-23, functionally replaces SNAP-25 in the SNARE complex. Studies show that VAMP, syntaxin and SNAP-23 are required for SNARE function and that this complex exists as a heterotrimer of the three proteins. In insulin signalling pathways, studies suggest that the translocation of GLUT4 in adipocytes requires that functional SNAP-23 be present in SNARE complexes.Synonyms: SNAP-23, Synaptosomal-associated protein 23, Vesicle-membrane fusion protein SNAP-23

Poids moléculaire: 23.4kDa (NP_003816.2

ID gène: 8773

NCBI Accession: NP_003816

UniProt: O00161