AP2M1 anticorps (C-Term)

N° du produit ABIN499285

Détail du produit anti-AP2M1 anticorps

Antigène: AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp AP2M1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to AP2M1.

Purification: Affinity chromatography purified via peptide column

Immunogène: AP2M1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human AP2M1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: AP2M1 antibody can be used for detection of AP2M1 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur AP2M1

Antigène: AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))

Abstract: AP2M1 Produits

Synonymes: anticorps AP50, anticorps CLAPM1, anticorps mu2, anticorps Ap50, anticorps Clapm1, anticorps cb34, anticorps Ap2m1, anticorps dpy-23, anticorps sb:cb34, anticorps zgc:55711, anticorps zgc:85653, anticorps wu:fa97a10, anticorps ap2m1-a, anticorps ap2m1, anticorps zgc:56643, anticorps AP2M1, anticorps adaptor related protein complex 2 mu 1 subunit, anticorps adaptor-related protein complex 2, mu 1 subunit, anticorps adaptor-related protein complex 2, mu 1 subunit, a, anticorps adaptor related protein complex 2 mu 1 subunit L homeolog, anticorps adaptor-related protein complex 2, mu 1 subunit, b, anticorps AP-2 complex subunit mu-1, anticorps clathrin coat assembly protein AP50, anticorps clathrin coat assembly protein ap50, anticorps AP2M1, anticorps Ap2m1, anticorps ap2m1a, anticorps ap2m1.L, anticorps ap2m1b, anticorps ap2m1, anticorps cgd8_950, anticorps PY06523, anticorps PVX_118455, anticorps PVX_123590, anticorps CpipJ_CPIJ003697

Sujet: The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.Synonyms: AP-2 mu-2 chain, Adaptin-mu2, CLAPM1, Clathrin assembly protein complex 2 medium chain, Clathrin coat assembly protein AP50, Clathrin coat-associated protein AP5, HA2 50 kDa subunit, KIAA0109, Plasma membrane adaptor AP-2 50 kDa protein

ID gène: 1173

NCBI Accession: NP_004059

UniProt: Q96CW1

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation, SARS-CoV-2 Protein Interactome