CADPS anticorps (C-Term)

N° du produit ABIN499523

L’anticorps Lapin Polyclonal anti-CADPS a été validé pour WB, IHC (p) et EIA. Il convient pour détecter CADPS dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CADPS anticorps (C-Term) (ABIN499523)

Antigène: CADPS (Ca++-Dependent Secretion Activator (CADPS))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CADPS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-CADPS anticorps

Épitope: C-Term

Specificité: This antibody reacts to CAPS1.

Purification: Affinity chromatography purified via peptide column

Immunogène: CAPS1 antibody was raised against a 20 amino acid peptide near the carboxy terminus of the human CAPS1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CAPS1 antibody can be used for detection of CAPS1 at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CADPS

Antigène: CADPS (Ca++-Dependent Secretion Activator (CADPS))

Autre désignation: CADPS

Sujet: CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles, CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion. Numerous isoforms of CAPS1 are known to exist, the lower molecular weight bands seen in the immunoblot image are likely to be these isoforms. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.Synonyms: CAPS, CAPS-1, CAPS1, Calcium-dependent activator protein for secretion 1, Calcium-dependent secretion activator 1, KIAA1121

ID gène: 8618

NCBI Accession: NP_899631

UniProt: Q9ULU8

Pathways: Synaptic Vesicle Exocytosis