FNIP2 anticorps (C-Term)

N° du produit ABIN499853

Détail du produit anti-FNIP2 anticorps

Antigène: FNIP2 (Folliculin Interacting Protein 2 (FNIP2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FNIP2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to FNIP2.

Purification: Affinity chromatography purified via peptide column

Immunogène: FNIP2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human FNIP2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur FNIP2

Antigène: FNIP2 (Folliculin Interacting Protein 2 (FNIP2))

Autre désignation: FNIP2 (FNIP2 Produits)

Synonymes: anticorps LOC797213, anticorps FNIPL, anticorps MAPO1, anticorps D630023B12Rik, anticorps mKIAA1450, anticorps RGD1562174, anticorps folliculin interacting protein 2, anticorps si:ch211-42i9.8, anticorps FNIP2, anticorps si:ch211-42i9.8, anticorps fnip2, anticorps Fnip2

Sujet: FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49 % identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship. Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.Synonyms: FNIP1-like protein, FNIPL, Folliculin-interacting protein 2, KIAA1450, MAPO1, O6-methylguanine-induced apoptosis 1 protein

ID gène: 57600

NCBI Accession: NP_065891

UniProt: Q9P278