IL23A anticorps (C-Term)

N° du produit ABIN499996

Cet anticorps Lapin Polyclonal détecte spécifiquement IL23A dans WB, IF et EIA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour IL23A anticorps (C-Term) (ABIN499996)

Antigène: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL23A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-IL23A anticorps

Épitope: C-Term

Specificité: This antibody reacts to IL-23.

Purification: Affinity chromatography purified via peptide column

Immunogène: IL-23 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IL-23.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western BLot: 2 - 4 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur IL23A

Antigène: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Autre désignation: Interleukin-23 alpha / IL23A

Sujet: Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF

ID gène: 51561

UniProt: Q9NPF7

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation