Cytochrome C anticorps

N° du produit ABIN5000922

Cet anticorps Souris Monoclonal détecte spécifiquement Cytochrome C dans WB, IHC (p) et IF (p). Il présente une réactivité envers Humain, Rat et Lapin et a été mentionné dans 1 publication.

Aperçu rapide pour Cytochrome C anticorps (ABIN5000922)

Antigène: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Reactivité: Humain, Rat, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytochrome C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: 6B10

Détail du produit anti-Cytochrome C anticorps

Réactivité croisée: Humain, Lapin, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant human Cytochrome C Protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Cytochrome C (ABIN5000922)

Ding, Chen, Wu, Chen, Zhang, Fan, Wang, Ji, Xie, Ning, Shen: "Increased expression of HERPUD1 involves in neuronal apoptosis after intracerebral hemorrhage." dans: Brain research bulletin, Vol. 128, pp. 40-47, (2016) (PubMed).

Détails sur Cytochrome C

Antigène: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Autre désignation: Cytochrome C

Sujet:

Synonyms: Cytochrome c, CYCS

Background: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

ID gène: 54205

UniProt: P99999

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity