FOXO4 anticorps (pThr451) (AbBy Fluor® 680)

N° du produit ABIN5002861

L’anticorps Lapin Polyclonal anti-FOXO4 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter FOXO4 dans des échantillons de Humain et Rat.

Aperçu rapide pour FOXO4 anticorps (pThr451) (AbBy Fluor® 680) (ABIN5002861)

Antigène: FOXO4 (Forkhead Box O4 (FOXO4))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO4 est conjugé à/à la AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-FOXO4 anticorps (AbBy Fluor® 680)

Épitope: pThr451

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human FOXO4 around the phosphorylation site of Thr451

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FOXO4

Antigène: FOXO4 (Forkhead Box O4 (FOXO4))

Autre désignation: FOXO4

Sujet:

Synonyms: FOXO4 phospho T451,p-FOXO4 phospho T451, AFXSer197, Fork head domain transcription factor AFX1, AFX, AFX1, Afxh, ALL1-fused gene from X chromosome, Fork head domain transcription factor AFX1, Forkhead box O4, Forkhead box protein O4, FOXO 4, Mixed lineage leukemia, translocated to, 7, MLLT7, Myeloid lymphoid or mixed lineage leukemia translocated to 7, Myeloid/lymphoid or mixed lineage leukemia, translocated to, 7, Putative fork head domain transcription factor AFX1, FOXO4_HUMAN.

Background: FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.

ID gène: 4303

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation