MAP3K14 anticorps (C-Term)

N° du produit ABIN500347

Détail du produit anti-MAP3K14 anticorps

Antigène: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Épitope: AA 931-947, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K14 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects MAP3K14 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: DEAE purified

Immunogène: NIK antibody was raised against a peptide corresponding to amino acids 931 to 947 of human NIK.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur MAP3K14

Antigène: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Autre désignation: MAP3K14 (MAP3K14 Produits)

Synonymes: anticorps FTDCR1B, anticorps HS, anticorps HSNIK, anticorps NIK, anticorps F23F1.4, anticorps F23F1_4, anticorps mitogen-activated protein kinase kinase kinase 14, anticorps Nik, anticorps aly, anticorps mitogen-activated protein kinase kinase kinase 14, anticorps MAP3K14, anticorps Map3k14, anticorps MAPKKK14

Sujet: Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha, LPS and mitogens. A serine/threonine protein kinase which mediates NF-kappaB activation by IL-1, TNFalpha and CD95 was identified recently and designated NIK (for NF-kappaB inducing kinase) . NIK is an activator of IkappaB kinase alpha and beta (IKKalpha and IKKbeta). Therefore, NIK is a key molecule in the NF-kappaB signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products.Synonyms: Mitogen-activated protein kinase kinase kinase 14, NF-kappa beta-inducing kinase, Serine/threonine-protein kinase NIK

ID gène: 9020

UniProt: Q99558

Pathways: Signalisation NF-kappaB, TCR Signaling