RHBDD1 anticorps (C-Term)

N° du produit ABIN500589

Détail du produit anti-RHBDD1 anticorps

Antigène: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHBDD1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogène: RHBDD1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human RHBDD1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur RHBDD1

Antigène: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Autre désignation: RHBDD1 (RHBDD1 Produits)

Synonymes: anticorps MGC84665, anticorps RRP4, anticorps 4930418P06Rik, anticorps mRHBDD1, anticorps RGD1306477, anticorps rRHBDD1, anticorps rhomboid domain containing 1, anticorps rhomboid domain containing 1 L homeolog, anticorps RHBDD1, anticorps rhbdd1.L, anticorps rhbdd1, anticorps Rhbdd1

Sujet: The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD1 is highly expressed in the testis and is involved in the cleavage of BIK, a proapoptotic member of the Bcl-2 family. Overexpression or suppression by RNAi of RHBDD1 in 293 cells will reduce or enhance BIK-mediated apoptosis, respectively, demonstrating that RHBDD1 modulates BIK-mediated apoptotic activity. In GC-1 cells, a spermatogonia cell line that can differentiate into spermatids within the seminiferous tubules, suppression of RHBDD1 expression by RNAi caused the cells to lose the ability to survive and differentiate in mouse seminiferous tubules, suggesting that RHBDD1 may be associated with mammalian spermatogenesis.Synonyms: HSD-50, HSD50, Rhomboid domain-containing protein 1

ID gène: 84236

UniProt: Q8TEB9