RHBDD1 anticorps (C-Term)

N° du produit ABIN6990162

Détail du produit anti-RHBDD1 anticorps

Antigène: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHBDD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: RHBDD1 Antibody is affinity chromatography purified via peptide column.

Immunogène: RHBDD1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human RHBDD1. The immunogen is located within the last 50 amino acids of RHBDD1.

Isotype: IgG

Information d'application

Indications d'application: RHBDD1 antibody can be used for detection of RHBDD1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RHBDD1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: RHBDD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RHBDD1

Antigène: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Autre désignation: RHBDD1 (RHBDD1 Produits)

Synonymes: anticorps MGC84665, anticorps RRP4, anticorps 4930418P06Rik, anticorps mRHBDD1, anticorps RGD1306477, anticorps rRHBDD1, anticorps rhomboid domain containing 1, anticorps rhomboid domain containing 1 L homeolog, anticorps RHBDD1, anticorps rhbdd1.L, anticorps rhbdd1, anticorps Rhbdd1

Sujet: RHBDD1 Antibody: The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD1 is highly expressed in the testis and is involved in the cleavage of BIK, a proapoptotic member of the Bcl-2 family. Overexpression or suppression by RNAi of RHBDD1 in 293 cells will reduce or enhance BIK-mediated apoptosis, respectively, demonstrating that RHBDD1 modulates BIK-mediated apoptotic activity. In GC-1 cells, a spermatogonia cell line that can differentiate into spermatids within the seminiferous tubules, suppression of RHBDD1 expression by RNAi caused the cells to lose the ability to survive and differentiate in mouse seminiferous tubules, suggesting that RHBDD1 may be associated with mammalian spermatogenesis.

ID gène: 84236

UniProt: Q8TEB9