RHBDD1 anticorps (AA 62-293)

N° du produit ABIN7876156

Cet anticorps anti-RHBDD1 Polyclonal Lapin (ABIN7876156) détecte spécifiquement RHBDD1 dans WB, ELISA, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour RHBDD1 anticorps (AA 62-293) (ABIN7876156)

Antigène: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHBDD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RHBDD1 anticorps

Épitope: AA 62-293

Fonction: RRP4 Antibody / EXOSC2

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids R62-G293) was used as the immunogen for the RRP4 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RRP4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the RRP4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur RHBDD1

Antigène: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Autre désignation: RRP4

Sujet: Exosome component 2, also known as Exosome complex component RRP4 and EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snoRNA and snRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. EXOSC2 is a non-catalytic component of the RNA exosome complex that has 3'->5' exoribonuclease activity and involves in a multitude of cellular RNA processing and degradation events.

UniProt: Q13868