PEN2 anticorps (AA 6-80) (AbBy Fluor® 680)

N° du produit ABIN5008661

Cet anticorps anti-PEN2 est un anticorps Lapin Polyclonal détectant PEN2 dans WB, IF (cc) et IF (p). Adapté pour Souris et Rat.

Aperçu rapide pour PEN2 anticorps (AA 6-80) (AbBy Fluor® 680) (ABIN5008661)

Antigène: PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEN2 est conjugé à/à la AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PEN2 anticorps (AbBy Fluor® 680)

Épitope: AA 6-80

Specificité: Belongs to the PEN-2 family

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PEN2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PEN2

Antigène: PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

Autre désignation: PEN2

Sujet:

Synonyms: PEN2, PEN-2, MDS033, MSTP064, Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, PSENEN

Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.

ID gène: 55851

UniProt: Q9NZ42

Pathways: Signalisation Notch, Neurotrophin Signaling Pathway