TLR10 anticorps (Center)
Aperçu rapide pour TLR10 anticorps (Center) (ABIN500940)
Antigène
Voir toutes TLR10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Ion exchange chromatography
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Immunogène
- TLR10 antibody was raised against a peptide corresponding to 14 amino acids near the middle of human TLR10.
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Isotype
- IgG
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Indications d'application
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ELISA. Western blot: 0.5 to 1 μg/mL. Despite its predicted size of approx. 90 kDa, a band correpsondingto TLR10 is observed at approx. 75 kDa in immunoblot assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- TLR10 (Toll-Like Receptor 10 (TLR10))
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Autre désignation
- CD290 / TLR10
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Sujet
- Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR10 is highly homologous to TLRs 1 and 6 and is most highly expressed in lymphoid tissues (6). Most recently genetic variation in TLR10 has been associated with contributing to asthma risk (7). It should be noted that TLR10 exists in mice only as a pseudogene (8).Synonyms: Toll-like receptor 10, UNQ315/PRO358
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ID gène
- 81793
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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